Saturday, April 16

Last minute quick view - Viral Hepatitis

Assalamualaikum. In the name of Allah, the Most Beneficent, the most Merciful.

Characteristics of Hepatitis Viruses
Desease
Component of System & their Definition
Hepatitis A
HAV → Hepatitis A virus. Etiologic agent of infectious hepatitis. A picornavirus, the prototype of genus Hepatovirus.
Anti-HAV → Antibody to HAV. Detectable at onset ot symptoms; lifetime persistence. :D
IgM anti-HAV → IgM class antibody to HAV. Indicates recent infection with hepatitis A; positive up to 4-6 months after infection.
Hepatitis B
HBV → Hepatitis B virus. Etiologic agent of serum hepatitis. A hepadna virus.
HBsAg → Hepatitis B surface antigen. Surface antigen(s) of HBV detectable in large quantity in serum; several subtypes identified.
HBeAg → Hepatitis B e antigen. Associated with HBV nucleocapsid; indicates viral replication; circulates as soluble antigen in serum.
HBcAg → Hepatitis C core antigen.
Anti-HBs → Antibody to HBeAg. Indicates past infection with and immunity to HBV, presence of passive antibody from HBIG, or immune response from HBV vaccine.
Anti-HBe → Antibody to HBeAg. Presence in serum of HBsAg carrier suggests low titer of HBV.
Anti-HBc → Antibody to HBcAg. Indicates infection with HBV at some undefined time in the past.
IgM anti-HBc → IgM class antibody to HBcAg. Indicates recent infection with HBV; positive for 4-6 months after infection.
Hepatitis C
HCV →  Hepatitis C virus, a common etiologic agent of posttransfusion hepatitis. A flavivirus, genus Hepacivirus.
Anti-HCV → Antibody to HCV
Hepatitis D
HDV → Hepatitis D virus. Etiologic agent of delta hepatitis; causes infection only in presence of HBV.
HDAg → Delta antigen (delta-Ag). Detectable in early acute HDV infection.
Anti-HDV → Antibody to delta-Ag (anti-delta). Indicates past or present infection infection with HDV.
Hepatitis E
HEV → Hepatitis V virus. Enterically transmitted hepatitis virus. Cause large epidemics in Asia, North and West Africa, and Mexico; fecal-oral or water-borne transmission. Unclassified.
Immune globulins
IG → Immune globulin USP. Contains antibodies to HAV; no antibodies to HBsAg, HCV, or HIV
HBIG → Hepatitis B immune globulin. Contains high titers of antibodies to HBV.

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